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Ligne 15 : | Ligne 15 : | ||
I: Integration | I: Integration | ||
− | + | # Collective structuring | |
− | + | # In space: From sub-nano, to meso, to macro | |
− | + | # In time: Modulation of structures, oscillations | |
− | + | # Emergence of new properties because of the network topologies (feedback loops) | |
− | + | # Emergence of new functions | |
Ligne 25 : | Ligne 25 : | ||
:Specificity of interactions and integrations | :Specificity of interactions and integrations | ||
− | + | # From bimolecular recognition (host-guest) to large self-assemblies | |
− | + | # Hierarchy of self-assemblies | |
:Dynamics is important and can take place at the three levels M, I, and I. | :Dynamics is important and can take place at the three levels M, I, and I. | ||
In time and space | In time and space | ||
− | + | # Conformational Dynamic | |
− | + | # Constitutional dynamic: reversibility of the structure of the systems components | |
− | + | # Network dynamics in coupled reactions | |
− | + | # Reversible dynamics at the three levels allow adaptation | |
:Reversibility is an important requirement for evolvability | :Reversibility is an important requirement for evolvability | ||
− | + | # Creates stocastic behavior for exploration of phenotypes | |
− | + | # Generate adaptativity by "mutations" which are driven by internal, or environmental parameters (e.g. stimuli, effectors) | |
:Cooperativity is part of the integration processes which is important for modulations | :Cooperativity is part of the integration processes which is important for modulations | ||
− | + | # Allosteric effects | |
− | + | # Long range interactions and colective behaviors (e.g. phase transitions) | |
− | + | # Auto-catalysis and cross-catalysis | |
− | + | # Cooperativity allows emergence | |
Ligne 53 : | Ligne 53 : | ||
:New functions | :New functions | ||
:Open questions | :Open questions | ||
− | + | # Is supramolecular complexity (one of the) the support to produce thinking matter? | |
− | + | # If yes, is this pathway continuous or does it present at one point a strong nonlinearity in evolution? Information/consciousness? | |
::Possible Applications and societal implications | ::Possible Applications and societal implications | ||
:Medicine | :Medicine | ||
− | + | # Drugs | |
− | + | # Transfections - Delivery | |
− | + | # Imaging | |
:Celullar biology | :Celullar biology | ||
− | + | # Understanding of the construction of molecular networks | |
− | + | # Understanding protein foldings | |
− | + | # Biomimetic behaviors | |
:Environmental sciences | :Environmental sciences | ||
− | + | # CO2 capture | |
− | + | # Water purification | |
:Chemistry and materials | :Chemistry and materials | ||
− | + | # Catalysis | |
− | + | # Organic electronics | |
− | + | # Solar cells | |
− | + | # Self-healing materials | |
− | + | # Smart materials (responsive/adaptive) | |
− | + | # Information processing and engineering | |
::Teaching complex systems in chemistry (Strasbourg Erasmus Mundus) | ::Teaching complex systems in chemistry (Strasbourg Erasmus Mundus) |
Version du 19 janvier 2012 à 15:41
Rédacteurs: Nicolas Giuseppone, Mario Ruben, Mihail Stadler, Franck Hoonakker, Emilie Moulin, Jean-Marc Planeix, Mourad Elhabiri, (Ali Trabolsi)
- Definition of complexity
- C = MxIxI
M: Multiplicity;
- One single molecule can present several properties e.g. Multiplicity of binding sites, number of energy levels....
- Mutiplicity of components: number of components (molecular) /constituents (supramolecular) in the system
I: Interaction
- Complentaries of shapes, of charges, of energy levels (Program writing / reading)
- Thermodynamic and kinetic of the interaction (reversibility, lability), covalent / non-covalent bonds, short-range/long-range
C/ Interactions of molecules with their environments (possibly in flux of energies far from equilibrium)
I: Integration
- Collective structuring
- In space: From sub-nano, to meso, to macro
- In time: Modulation of structures, oscillations
- Emergence of new properties because of the network topologies (feedback loops)
- Emergence of new functions
- Characteristics for supramolecular complexity
- Specificity of interactions and integrations
- From bimolecular recognition (host-guest) to large self-assemblies
- Hierarchy of self-assemblies
- Dynamics is important and can take place at the three levels M, I, and I.
In time and space
- Conformational Dynamic
- Constitutional dynamic: reversibility of the structure of the systems components
- Network dynamics in coupled reactions
- Reversible dynamics at the three levels allow adaptation
- Reversibility is an important requirement for evolvability
- Creates stocastic behavior for exploration of phenotypes
- Generate adaptativity by "mutations" which are driven by internal, or environmental parameters (e.g. stimuli, effectors)
- Cooperativity is part of the integration processes which is important for modulations
- Allosteric effects
- Long range interactions and colective behaviors (e.g. phase transitions)
- Auto-catalysis and cross-catalysis
- Cooperativity allows emergence
- Consequences of supramolecular complexity
- Diversity
- Selection
- Evolution
- New functions
- Open questions
- Is supramolecular complexity (one of the) the support to produce thinking matter?
- If yes, is this pathway continuous or does it present at one point a strong nonlinearity in evolution? Information/consciousness?
- Possible Applications and societal implications
- Medicine
- Drugs
- Transfections - Delivery
- Imaging
- Celullar biology
- Understanding of the construction of molecular networks
- Understanding protein foldings
- Biomimetic behaviors
- Environmental sciences
- CO2 capture
- Water purification
- Chemistry and materials
- Catalysis
- Organic electronics
- Solar cells
- Self-healing materials
- Smart materials (responsive/adaptive)
- Information processing and engineering
- Teaching complex systems in chemistry (Strasbourg Erasmus Mundus)