Différences entre les versions de « F1 - Supramolecular Systems »
| Ligne 1 : | Ligne 1 : | ||
Rédacteurs: Nicolas Giuseppone, Mario Ruben, Mihail Stadler, Franck Hoonakker, Emilie Moulin, Jean-Marc Planeix, Mourad Elhabiri, (Ali Trabolsi) | Rédacteurs: Nicolas Giuseppone, Mario Ruben, Mihail Stadler, Franck Hoonakker, Emilie Moulin, Jean-Marc Planeix, Mourad Elhabiri, (Ali Trabolsi) | ||
| − | Definition of complexity | + | ::Definition of complexity |
| − | C = MxIxI | + | :C = MxIxI |
M: Multiplicity; | M: Multiplicity; | ||
| Ligne 22 : | Ligne 22 : | ||
| − | Characteristics for supramolecular complexity | + | ::Characteristics for supramolecular complexity |
| − | Specificity of interactions and integrations | + | :Specificity of interactions and integrations |
A/ From bimolecular recognition (host-guest) to large self-assemblies | A/ From bimolecular recognition (host-guest) to large self-assemblies | ||
B/ Hierarchy of self-assemblies | B/ Hierarchy of self-assemblies | ||
| − | Dynamics is important and can take place at the three levels M, I, and I. | + | :Dynamics is important and can take place at the three levels M, I, and I. |
In time and space | In time and space | ||
A/ Conformational Dynamic | A/ Conformational Dynamic | ||
| Ligne 35 : | Ligne 35 : | ||
D/ Reversible dynamics at the three levels allow adaptation | D/ Reversible dynamics at the three levels allow adaptation | ||
| − | Reversibility is an important requirement for evolvability | + | :Reversibility is an important requirement for evolvability |
A/ Creates stocastic behavior for exploration of phenotypes | A/ Creates stocastic behavior for exploration of phenotypes | ||
B/ Generate adaptativity by "mutations" which are driven by internal, or environmental parameters (e.g. stimuli, effectors) | B/ Generate adaptativity by "mutations" which are driven by internal, or environmental parameters (e.g. stimuli, effectors) | ||
| − | Cooperativity is part of the integration processes which is important for modulations | + | :Cooperativity is part of the integration processes which is important for modulations |
A/ Allosteric effects | A/ Allosteric effects | ||
B/ Long range interactions and colective behaviors (e.g. phase transitions) | B/ Long range interactions and colective behaviors (e.g. phase transitions) | ||
| Ligne 46 : | Ligne 46 : | ||
| − | :Consequences of supramolecular complexity | + | ::Consequences of supramolecular complexity |
GGGG | GGGG | ||
| − | Possible Applications and societal implications | + | ::Possible Applications and societal implications |
| − | Teaching complex systems in chemistry (Strasbourg Erasmus Mundus) | + | ::Teaching complex systems in chemistry (Strasbourg Erasmus Mundus) |
Version du 19 janvier 2012 à 15:14
Rédacteurs: Nicolas Giuseppone, Mario Ruben, Mihail Stadler, Franck Hoonakker, Emilie Moulin, Jean-Marc Planeix, Mourad Elhabiri, (Ali Trabolsi)
- Definition of complexity
- C = MxIxI
M: Multiplicity; A/ One single molecule can present several properties e.g. Multiplicity of binding sites, number of energy levels.... B/ Mutiplicity of components: number of components (molecular) /constituents (supramolecular) in the system
I: Interaction A/ Complentaries of shapes, of charges, of energy levels (Program writing / reading) B/ Thermodynamic and kinetic of the interaction (reversibility, lability), covalent / non-covalent bonds, short-range/long-range C/ Interactions of molecules with their environments (possibly in flux of energies far from equilibrium)
I: Integration A/ Collective structuring B/ In space: From sub-nano, to meso, to macro C/ In time: Modulation of structures, oscillations D/ Emergence of new properties because of the network topologies (feedback loops) E/ Emergence of new functions
- Characteristics for supramolecular complexity
- Specificity of interactions and integrations
A/ From bimolecular recognition (host-guest) to large self-assemblies B/ Hierarchy of self-assemblies
- Dynamics is important and can take place at the three levels M, I, and I.
In time and space A/ Conformational Dynamic B/ Constitutional dynamic: reversibility of the structure of the systems components C/ Network dynamics in coupled reactions D/ Reversible dynamics at the three levels allow adaptation
- Reversibility is an important requirement for evolvability
A/ Creates stocastic behavior for exploration of phenotypes B/ Generate adaptativity by "mutations" which are driven by internal, or environmental parameters (e.g. stimuli, effectors)
- Cooperativity is part of the integration processes which is important for modulations
A/ Allosteric effects B/ Long range interactions and colective behaviors (e.g. phase transitions) C/ Auto-catalysis and cross-catalysis D/ Cooperativity allows emergence
- Consequences of supramolecular complexity
GGGG
- Possible Applications and societal implications
- Teaching complex systems in chemistry (Strasbourg Erasmus Mundus)